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Article

Childhood trauma, suicide risk and inflammatory phenotypes of depression: insights from monocyte gene expression.

Translational psychiatry - 24 Aug 2020

Schiweck Carmen, Claes Stephan, Van Oudenhove Lukas, Lafit Ginette, Vaessen Thomas, de Beeck Gommaar Op, Berghmans Raf, Wijkhuijs Annemarie, Müller Norbert, Arolt Volker, Drexhage Hemmo, Vrieze Elske

Abstract excerpt

Circulating monocytes contribute to inflammatory processes. We here validate abnormal expression of inflammation-related genes in monocytes of a large and well-characterised group of MDD patients, and relate the outcomes to pertinent clinical characteristics. Thirty-two genes of a previously established inflammation-related gene signature were assessed in 197 patients with MDD, and 151 controls collected during...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32839428
DOI: 10.1038/s41398-020-00979-z
PMCID: PMC7445278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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