Article
Impact of gene-by-trauma interaction in MDD-related multimorbidity clusters.
Journal of affective disorders - 15 Aug 2024
Bonk Sarah, Eszlari Nora, Kirchner Kevin, Gezsi Andras, Garvert Linda, Kuokkanen Mikko, Cano Isaac, Grabe Hans J, Antal Peter, Juhasz Gabriella, Van der Auwera Sandra
Abstract excerpt
BACKGROUND: Major depressive disorder (MDD) is considerably heterogeneous in terms of comorbidities, which may hamper the disentanglement of its biological mechanism. In a previous study, we classified the lifetime trajectories of MDD-related multimorbidities into seven distinct clusters, each characterized by unique genetic and environmental risk-factor profiles. The current objective was to investigate...
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