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Article

Elevated C-Reactive Protein in Patients With Depression, Independent of Genetic, Health, and Psychosocial Factors: Results From the UK Biobank.

The American journal of psychiatry - 1 Jun 2021

Pitharouli Maria C, Hagenaars Saskia P, Glanville Kylie P, Coleman Jonathan R I, Hotopf Matthew, Lewis Cathryn M, Pariante Carmine M

Abstract excerpt

OBJECTIVE: The authors investigated the pathways (genetic, environmental, lifestyle, medical) leading to inflammation in major depressive disorder using C-reactive protein (CRP), genetic, and phenotypic data from the UK Biobank. METHODS: This was a case-control study of 26,894 participants with a lifetime diagnosis of major depressive disorder from the Composite International Diagnostic Interview and 59,001...

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Identifiers

PMID: 33985349
DOI: 10.1176/appi.ajp.2020.20060947

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