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Cumulative pregnancy and postnatal environmental exposures impact social behaviour in male mice associated with epigenetic, ribosomal, and immune dysregulation

2025-03-19

Abstract excerpt

Environmental exposures across critical developmental windows can significantly influence brain development and contribute to the pathogenesis of neurodevelopmental disorders (NDDs). Emerging clinical evidence suggests that cumulative environmental factors during early development result in more pronounced disease phenotypes in offspring. Here, we developed a ‘triple-hit’ model using C57Bl/6JAusb mice to examine t...

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Literature Corpus work
f773f414-4743-5ce9-a4e7-82f009dd2f62
DOI
10.1101/2025.03.19.644073
Open publication

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Cumulative pregnancy and postnatal environmental exposures impact social behaviour in male mice associated with epigenetic, ribosomal, and immune dysregulationDOI 10.1101/2025.03.19.644073
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