Article
Genetic Mapping of Behavioral Traits Using the Collaborative Cross Resource.
International journal of molecular sciences - 30 Dec 2022
Xuan Wei, Zhang Ling, Zhang Yu, Sun Xiuping, Wang Jue, Li Xianglei, Zhang Lingyan, Wang Xinpei, Morahan Grant, Qin Chuan
Abstract excerpt
The complicated interactions between genetic background, environment and lifestyle factors make it difficult to study the genetic basis of complex phenotypes, such as cognition and anxiety levels, in humans. However, environmental and other factors can be tightly controlled in mouse studies. The Collaborative Cross (CC) is a mouse genetic reference population whose common genetic and phenotypic diversity is on...
Topics
- Humans
- Mice
- Animals
- Chromosome Mapping
- Quantitative Trait Loci
- Phenotype
- Genomics
- Genetics, Population
- Crosses, Genetic
