Article
Paternal nicotine taking elicits heritable sex-specific phenotypes that are mediated by hippocampal Satb2.
Molecular psychiatry - 1 Sept 2022
Maurer John J, Wimmer Mathieu E, Turner Christopher A, Herman Rae J, Zhang Yafang, Ragnini Kael, Ferrante Julia, Kimmey Blake A, Crist Richard C, Christopher Pierce R, Schmidt Heath D
Abstract excerpt
Nicotine intake, whether through tobacco smoking or e-cigarettes, remains a global health concern. An emerging preclinical literature indicates that parental nicotine exposure produces behavioral, physiological, and molecular changes in subsequent generations. However, the heritable effects of voluntary parental nicotine taking are unknown. Here, we show increased acquisition of nicotine taking in male and female...
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