Article
DAESC + : high-performance, integrated software for single-cell allele-specific expression data.
BMC bioinformatics - 18 Mar 2026
Cui Tengfei, Qi Guanghao
Abstract excerpt
Single-cell allele-specific expression (ASE) provides valuable insights into gene regulatory mechanisms. However, its utility is limited by the lack of dedicated computational tools. We present DAESC + , a dual-module end-to-end software package for the processing and analysis of single-cell ASE. The preprocessing module, DAESC-P, is a user-friendly bioinformatics pipeline to obtain ASE counts from multiplexed...
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