Article
Uniform Processing of Diverse Sequencing Data: A Cross-Population Comparison of Colon Cancer Genomic Landscapes from The Cancer Genome Atlas and a Chinese Cohort.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2026
Chang Hsin-Yu, Huang Chien-Jung, Yeh Yi-Chen, Wang Yu-Chao
Abstract excerpt
BACKGROUND: Colon cancer is genetically heterogeneous, necessitating standardized genomic analyses for cross-cohort comparisons. Although The Cancer Genome Atlas-colon adenocarcinoma (TCGA-COAD) is a widely used dataset, its comparability to other ethnically different populations remains unclear. This study systematically compares the genomic characteristics of TCGA-COAD and ChangKang, a Chinese colon cancer...
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