Article
Genome-wide association and sequencing studies on colorectal cancer.
Seminars in cancer biology - 1 Dec 2013
Wong Sunny H, Sung Joseph J Y, Chan Francis K L, To Ka F, Ng Simon S M, Wang Xiao J, Yu Jun, Wu William K K
Abstract excerpt
Colorectal cancer is a leading cause of morbidity and mortality worldwide. Understanding its genetic mechanisms is key to improving risk prediction, prognostication and treatment. Results from genome-wide association studies have engendered a growing list of colorectal cancer susceptibility genes whereas the application of genome-wide mutational analysis has enabled the depiction of mutational landscape of...
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