Next-Generation Sequencing-Based Analysis of the Genetic Mutation Spectrum in Colorectal Cancer: A Large Single‑Center Study From Southeast China With Cross‑Population Comparison.

Abstract excerpt

Colorectal cancer (CRC) exhibits considerable molecular heterogeneity. This study aimed to delineate the mutational landscape and investigate the associations between frequently mutated genes and key clinicopathological features in a single-center cohort of CRC patients using next-generation sequencing (NGS). This study included 381 patients with pathologically confirmed colorectal cancer. Tumor tissue samples...

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