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Article

Optical Molecular Signatures of IDH Genotype for Classification of Human Glioma Using Visible Resonance Raman Spectroscopy.

Journal of biophotonics - 1 Mar 2026

Zhang Liang, Zhou Yan, Wu Binlin, Zhang Shengjia, Zhu Ke, Liu Cheng-Hui, Alfano Robert, Yu Xinguang

Abstract excerpt

Glioma is the most common brain neoplasm that features aggressive behavior with a dismal prognosis. Isocitrate dehydrogenase (IDH) gene mutation in glioma is an early genetic event in gliomagenesis that occurs in virtually every tumor cell and can cause profound metabolic changes. In this manuscript, we report for the first time the analysis of Raman optical signatures of IDH genotypes for human glioma using...

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PMID: 41807088
DOI: 10.1002/jbio.70239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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