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Article

Intraoperative detection of IDH-mutant glioma using fluorescence lifetime imaging.

Journal of biophotonics - 1 Apr 2023

Noble Anbunesan Silvia, Alfonso-Garcia Alba, Zhou Xiangnan, Bec Julien, Lee Han Sung, Jin Lee-Way, Bloch Orin, Marcu Laura

Abstract excerpt

Identifying isocitrate dehydrogenase (IDH)-mutation and glioma subtype during surgery instead of days later can aid in modifying tumor resection strategies for better survival outcomes. We report intraoperative identification of IDH-mutant glioma (N = 12 patients) with a clinically compatible fluorescence lifetime imaging (FLIm) device (excitation: 355 nm; emission spectral bands: 390/40 nm, 470/28 nm,...

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Source

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Identifiers

PMID: 36510639
DOI: 10.1002/jbio.202200291
PMCID: PMC10522274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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