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Article

Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging.

Nature medicine - 1 Apr 2023

Hollon Todd, Jiang Cheng, Chowdury Asadur, Nasir-Moin Mustafa, Kondepudi Akhil, Aabedi Alexander, Adapa Arjun, Al-Holou Wajd, Heth Jason, Sagher Oren, Lowenstein Pedro, Castro Maria, Wadiura Lisa Irina, Widhalm Georg, Neuschmelting Volker, Reinecke David, von Spreckelsen Niklas, Berger Mitchel S, Hervey-Jumper Shawn L, Golfinos John G, Snuderl Matija, Camelo-Piragua Sandra, Freudiger Christian, Lee Honglak, Orringer Daniel A

Abstract excerpt

Molecular classification has transformed the management of brain tumors by enabling more accurate prognostication and personalized treatment. However, timely molecular diagnostic testing for patients with brain tumors is limited, complicating surgical and adjuvant treatment and obstructing clinical trial enrollment. In this study, we developed DeepGlioma, a rapid (<90 seconds), artificial-intelligence-based...

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Identifiers

PMID: 36959422
DOI: 10.1038/s41591-023-02252-4
PMCID: PMC10445531

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