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102 AI-Based Molecular Classification of Diffuse Gliomas using Rapid, Label-Free Optical Imaging.

Neurosurgery - 1 Apr 2023

Hollon Todd Charles, Golfinos John G, Orringer Daniel A, Berger Mitchel, Hervey-Jumper Shawn L, Muraszko Karin M, Freudiger Christian, Heth Jason, Sagher Oren, Jiang Cheng, Chowdury Asadur, Moin Mustafa Nasir, Kondepudi Akhil, Aabedi Alexander Arash, Adapa Arjun R, Al-Holou Wajd, Wadiura Lisa, Widhalm Georg, Neuschmelting Volker, Reinecke David, Camelo-Piragua Sandra

Abstract excerpt

INTRODUCTION: Molecular classification has transformed the management of brain tumors by enabling more accurate prognostication and personalized treatment. Access to timely molecular diagnostic testing for brain tumor patients is limited, complicating surgical and adjuvant treatment and obstructing clinical trial enrollment. METHODS: By combining stimulated Raman histology (SRH), a rapid, label-free,...

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PMID: 36924489
DOI: 10.1227/neu.0000000000002375_102

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