Somatic mutations from pathogenesis to forensic medicine: opportunities, challenges, and future directions.

Abstract excerpt

Somatic mutations, post-zygotic genetic alterations that accumulate throughout development and aging, generate intra-individual mosaicism that has traditionally been examined within oncology and developmental biology, but rarely contextualized for forensic practice. This review provides a critical forensic-centered synthesis of current biological evidence and sequencing technologies to evaluate whether, when, and...

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