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Article

Mucin stimulates the growth of Legionella pneumophila.

Microbiology (Reading, England) - 1 Mar 2026

Vargas Alexis, Kuhlemeier Hunter J, Cianciotto Nicholas P

Abstract excerpt

Previously, it was demonstrated that a chitinase (ChiA) secreted by the Legionella pneumophila type II secretion system (T2SS) degrades mucin, thereby facilitating bacterial movement through a mucin layer. Here, we discovered that the addition of mucin to a chemically defined medium (CDM) greatly stimulates the growth of L. pneumophila, indicating that the bacterium can very effectively utilize mucin as a food...

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Identifiers

PMID: 41770594
DOI: 10.1099/mic.0.001682
PMCID: PMC12952804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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