Article
Legionella pneumophila type II secretome reveals unique exoproteins and a chitinase that promotes bacterial persistence in the lung.
Proceedings of the National Academy of Sciences of the United States of America - 12 Dec 2006
DebRoy Sruti, Dao Jenny, Söderberg Maria, Rossier Ombeline, Cianciotto Nicholas P
Abstract excerpt
Type II protein secretion is critical for Legionella pneumophila infection of amoebae, macrophages, and mice. Previously, we found several enzymes to be secreted by this (Lsp) secretory pathway. To better define the L. pneumophila type II secretome, a 2D electrophoresis proteomic approach was use...
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