Article

Increased Low Molecular Weight Mucins in Muco-Obstructive Airway Disease Limit <i>Staphylococcus aureus</i> Growth

2025-12-04

Abstract excerpt

<h4>ABSTRACT</h4> Muco-obstructive airway diseases result in an increase in mucus accumulation and a decrease in mucus clearance. MUC5B is the most abundant secreted mucin in the human airways, and MUC5B mucin strands dimerize to create the mucus mesh network in the healthy respiratory tract. In muco-obstructive airway diseases like cystic fibrosis (CF), immune cells and bacteria release enzymes that degrade MUC5...

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Literature Corpus work: 32168698-dfa3-545c-9fe4-73796bcaff4e
DOI: 10.64898/2025.12.03.692258

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