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Article

Genetic variants of TLR4 and TLR9 are risk factors for chronic Helicobacter pylori infection in South Indian Tamils.

Human immunology - 1 Feb 2017

Loganathan Rekha, Nazeer Mehnaz, Goda Vaishnavi, Devaraju Panneer, Ali Mohammed, Karunakaran Premkumar, Jayaraman Megala

Abstract excerpt

Toll like receptors (TLRs) are a class of molecular pattern recognition receptors, elicits a strong inflammatory immune response against pathogens. Helicobacter pylori (H. pylori), a gram negative flagellate colonizes the human stomach, is responsible for the development of chronic gastritis and gastric carcinoma. The higher incidence of H. pylori infection and gastric cancer in South Indian Tamils demands a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27993530
DOI: 10.1016/j.humimm.2016.12.002

Genes

TLR4
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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