Article
Association of toll-like receptor 4, 5 and 10 polymorphisms with Helicobacter pylori-positive peptic ulcer disease in a center in Jordan.
Annals of Saudi medicine - 1 Jan 2000
Al-Eitan Laith, Almomani Fouad Abdelaziz, Al-Khatib Sohaib Mahmoud, Aljamal Hanan Abdulraheem, Al-Qusami Mohammed Nayef, Aljamal Rawan Abdulraheem
Abstract excerpt
BACKGROUND: Helicobacter pylori infection is widespread, affecting about 50% of the global population. Polymorphisms in host genes such as the toll-like receptor 4 (TLR4) might affect the susceptibility and severity of infection and treatment success. OBJECTIVE: Investigate the susceptibility and severity of H pylori infection with host TLR4 (rs11536889, rs4986790, rs200109652, rs10759932), TLR5 (rs5744174,...