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Article

Modulation of macrophage polarization with acute administration of Vericiguat after myocardial infarction.

American journal of physiology. Heart and circulatory physiology - 1 Mar 2026

Dempster Thomas, Corker Alexa, Vu Kim, Troncoso Miguel, Bradley Norma, Hazzard Amber, Milligan Kailee, Macaulay Bryce, Dasgupta Shaoni, Li Mei, DeLeon-Pennell Kristine Y

Abstract excerpt

Vericiguat (Merck, marketed as Verquvo) is a soluble guanylate cyclase stimulator that is Food and Drug Administration-approved for use in heart failure patients with reduced or mildly reduced ejection fraction (HFrEF and HFmrEF) to decrease heart failure hospitalization and cardiovascular mortality. We hypothesized that earlier administration of vericiguat post-myocardial infarction (MI) would reduce the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Ventricular Function, Left

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Identifiers

PMID: 41693664
DOI: 10.1152/ajpheart.00626.2025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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