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Article

Composite grey matter fingerprints for genetic frontotemporal dementia.

Journal of neurology, neurosurgery, and psychiatry - 12 Jun 2026

Bouzigues Arabella, Campana Giulia, Joulot Matthieu, Gensollen Nicolas, Russell Lucy L, Foster Phoebe H, Ferry-Bolder Eve, Van Swieten John Cornelis, Jiskoot Lize C, Seelaar Harro, Sánchez-Valle Raquel, Laforce Robert, Graff Caroline, Galimberti Daniela, Vandenberghe Rik, de Mendonca Alexandre, Tiraboschi Pietro, Santana Isabel, Gerhard Alexander, Levin Johannes, Sorbi Sandro, Otto Markus, Bertoux Maxime, Lebouvier Thibaud, Ducharme Simon, Butler Chris, Finger Elizabeth, Tartaglia Maria Carmela, Masellis Mario, Rowe James Benedict, Synofzik Matthis, Moreno Fermin, Borroni Barbara, Leber Isabelle, Zanusso Gianluigi, Rohrer Jonathan Daniel, Migliaccio Raffaella

Abstract excerpt

BACKGROUND: Brain structural changes in frontotemporal dementia (FTD) can occur decades before symptom onset. Precise characterisation of grey matter changes is necessary for developing models of biomarker progression, while better understanding the trajectory of the pathology is invaluable for prognosis and detecting treatment effects as we enter the era of clinical trials. METHODS: Cortical and subcortical grey...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41679970
DOI: 10.1136/jnnp-2025-337186
PMCID: PMC13288956

Genes

GRN
MAPT
C9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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