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Article

Gray matter changes in asymptomatic C9orf72 and GRN mutation carriers

1 Jan 2018

Abstract excerpt

Frontotemporal dementia (FTD) is a neurodegenerative disease with a strong genetic basis. Understanding the structural brain changes during pre-symptomatic stages may allow for earlier diagnosis of patients suffering from FTD; therefore, we investigated asymptomatic members of FTD families with mutations in C9orf72 and granulin (GRN) genes. Clinically asymptomatic subjects from families with C9orf72 mutation (15...

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PMID: 29845007
DOI: 10.1016/j.nicl.2018.02.017

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