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Article

Germline Variants in 32 Cancer-Related Genes among 700 Chinese Breast Cancer Patients by Next-Generation Sequencing: A Clinic-Based, Observational Study.

International journal of molecular sciences - 24 Sept 2022

Yang Liu, Xie Fei, Liu Chang, Zhao Jin, Hu Taobo, Wu Jinbo, Zhao Xiaotao, Wang Shu

Abstract excerpt

Breast cancer (BC) is associated with hereditary components, and some deleterious germline variants have been regarded as effective therapeutic targets. We conducted a clinic-based, observational study to better understand the distribution of deleterious germline variants and assess any clinicopathological predictors related to the variants among Chinese BC patients using a 32 cancer-related genes next-generation...

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Identifiers

PMID: 36232564
DOI: 10.3390/ijms231911266
PMCID: PMC9570072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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