Article
Targeted Next-generation Sequencing for Reliable Detection of Genetic Status in Breast Cancer.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP - 1 Jul 2021
Tariq Hassan, Gul Asma, Zubair Muhammad, Jaffer Syed Raza, Zafar Nadeem, Sadaf Ghazala
Abstract excerpt
OBJECTIVE: To test the germline oncogenic mutations in BRCA1 and BRCA2 genes, associated with triple-negative breast cancer (TNBC) patients under study, by targeted sequencing of their DNA with next-generation sequencing (NGS) platform. STUDY DESIGN: Cross-sectional observational study. PLACE AND DURATION OF STUDY: Histopathology Department, Armed Forces Institute of Pathology (AFIP) Rawalpindi, Pakistan from May...
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