BRCA1 and BRCA2 genes mutations among high risk breast cancer patients in Jordan.

doi:10.1038/s41598-020-74250-2

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BRCA1 and BRCA2 genes mutations among high risk breast cancer patients in Jordan.

Scientific reports - 16 Oct 2020

Abu-Helalah Munir, Azab Belal, Mubaidin Rasmi, Ali Dema, Jafar Hanan, Alshraideh Hussam, Drou Nizar, Awidi Abdalla

Abstract excerpt

Familial breast cancer is estimated to account for 15-20% of all cases of breast cancer. Surveillance for familial breast cancer is well-established world-wide. However, this service does not exist in Jordan, due to the scarcity of information with regard to the genetic profiling of these patients, and therefore lack of recommendations for policy-makers. As such, patients with very strong family history of breast...

Topics

Adult
Age of Onset
Aged
BRCA1 Protein
BRCA2 Protein
Breast Neoplasms
Breast Neoplasms, Male
DNA, Neoplasm
Early Detection of Cancer
Female
Genes, BRCA2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

High-Throughput Nucleotide Sequencing

Humans

Jordan

Male

Middle Aged

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 33067490
DOI: 10.1038/s41598-020-74250-2
PMCID: PMC7568559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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