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Article

Shared genetic architecture of obesity and gastroesophageal reflux disease.

Medicine - 6 Feb 2026

Xiao Lei, Zhu Dandan, Liu Wei

Abstract excerpt

Obesity is identified as a risk factor of gastroesophageal reflux disease (GERD). This study aims to elucidate the shared genetic architecture of obesity-related phenotypes and GERD. Based on the publicly available genome-wide association studies' datasets, this genome-wide pleiotropic association study was conducted with various genetic approaches (including linkage disequilibrium score regression,...

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Share to Bayes Theorem
Share to Body Mass Index
Share to Gastroesophageal Reflux

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 41650103
DOI: 10.1097/MD.0000000000047404
PMCID: PMC12885720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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