Article
GWA-based pleiotropic analysis identified potential SNPs and genes related to type 2 diabetes and obesity.
Journal of human genetics - 1 Mar 2021
Zeng Yong, He Hao, Zhang Lan, Zhu Wei, Shen Hui, Yan Yu-Jie, Deng Hong-Wen
Abstract excerpt
Metabolic syndrome is a cluster of symptoms including excessive body fat and insulin resistance which may lead to obesity and type 2 diabetes (T2D). The physiological and pathological cross-talk between T2D and obesity is crucial and complex, meanwhile, the genetic connection between T2D and obesity is largely unknown. The purpose of this study is to identify pleiotropic SNPs and genes between these two...
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