Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deposition of CENP-ACse4 is enhanced by mutations in the AAA+ ATPase domain of ATAD2Yta7.

Genetics - 4 Apr 2026

Kaur Navpreet, Cho Carol, Samel-Pommerencke Anke, Shahnejat-Bushehri Sara, Poßling Alexandra, Kuznecova Jolita, Song Ji-Joon, Ehrenhofer-Murray Ann E

Abstract excerpt

The chromatin remodeling factor and histone chaperone Yta7 is a member of the ATAD2 family of AAA+ ATPases from Saccharomyces cerevisiae that has in vivo functions consistent with both nucleosome assembly and disassembly activity. At the centromere, Yta7 is required for proper deposition of the centromeric histone H3 variant CENP-ACse4. Here, we performed a genetic screen to identify suppressors of the defect of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to ATPases Associated with Diverse Cellular Activities

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Centromere

Share to Chromosomal Proteins, Non-Histone

Share to Histones

Share to Nucleosomes

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 41642678
DOI: 10.1093/genetics/iyag035
PMCID: PMC13050212

Genes

ATAD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deposition of CENP-ACse4 is enhanced by mutations in the AAA+ ATPase domain of ATAD2Yta7.PMID 41642678Read ↗

Direct regulation of nucleosome density by the conserved AAA-ATPase Yta7.Semantic proximity Read ↗

The WAC-downWAC domain in the yeast ISW2 nucleosome remodeling complex forms a structural module essential for ISW2 function but not cell viabilitySemantic proximity Read ↗

An asymmetric centromeric nucleosome.Semantic proximity Read ↗

Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae.Semantic proximity Read ↗

Yra2 regulates proteolysis of Cse4 to prevent its mislocalization to non-centromeric regions for chromosomal stability in budding yeastSemantic proximity Read ↗

ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding.Semantic proximity Read ↗

Analysis of primary structural determinants that distinguish the centromere-specific function of histone variant Cse4p from histone H3.Semantic proximity Read ↗

A role for CENP-A/Cse4 phosphorylation on serine 33 in deposition at the centromere.Semantic proximity Read ↗

A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation.Semantic proximity Read ↗

Cse4 is part of an octameric nucleosome in budding yeast.Semantic proximity Read ↗

Acidic patch histone mutations and their effects on nucleosome remodeling.Semantic proximity Read ↗

Histone H2A is required for normal centromere function in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.