Article
Direct regulation of nucleosome density by the conserved AAA-ATPase Yta7.
Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 2011
Lombardi Laura M, Ellahi Aisha, Rine Jasper
Abstract excerpt
Yta7 is a highly conserved bromodomain-containing protein with AAA-ATPase homology originally implicated in heterochromatin boundary function in Saccharomyces cerevisiae. Although increased activity of the human ortholog has been implicated in malignant breast tumors, Yta7's precise mode of action is unknown. Transcriptional analysis in yeast cells revealed a role for Yta7 and its ATPase function in gene...
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