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Article

Clinical characteristics and prognostic outcomes in KRAS-mutant non-small cell lung cancer: A real-world study with or without COPD comorbidity.

Cancer treatment and research communications - 1 Jan 2026

Liao Chen, Wang Yubo, Bi Zhoukui, Chen Huawei, Xu Yu, Hu Defeng, Luo Rui, Wang Jiarui, Xu Zhi, Li Yafei, Bai Li

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the most prevalent comorbidity among lung cancer patients, but its clinical and prognostic relationship with KRAS-mutant non-small cell lung cancer (NSCLC) remains unclear. METHODS: This multicenter retrospective cohort study enrolled 163 histologically confirmed KRAS-mutant NSCLC patients, including 59 with COPD and 104 without COPD. Clinical data...

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Identifiers

PMID: 41633085
DOI: 10.1016/j.ctarc.2025.101064

Genes

KRAS

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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