Article
The prevalence and prognostic value of KRAS co-mutation subtypes in Chinese advanced non-small cell lung cancer patients.
Cancer medicine - 1 Jan 2020
Cai Dongjing, Hu Chengping, Li Li, Deng Shichao, Yang Jing, Han-Zhang Han, Li Min
Abstract excerpt
OBJECTIVE: KRAS mutation plays a critical role in the initiation and development of non-small cell lung cancer (NSCLC). KRAS-mutant patients exhibit diverse response to chemotherapy. KRAS co-mutation subtypes and their prognosis value in advanced Chinese NSCLC patients remain largely elusive. METHODS: A total of 1126 Chinese advanced NSCLC patients from Xiangya hospital were screened by capture-based ultra-deep...
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