Article
Hereditary ovarian cancer: beyond the usual suspects.
Gynecologic oncology - 1 Feb 2012
Pennington Kathryn P, Swisher Elizabeth M
Abstract excerpt
In the past, hereditary ovarian carcinoma was attributed almost entirely to mutations in BRCA1 and BRCA2, with a much smaller contribution from mutations in DNA mismatch repair genes. Recently, three new ovarian cancer susceptibility genes have been identified: RAD51C, RAD51D, and BRIP1. In addition, germline mutations in women with ovarian carcinoma have been recently identified in many of the previously...
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