Article
Adrenal histologic and genetic characteristics of primary aldosteronism in late adulthood.
European journal of endocrinology - 4 Feb 2026
Blinder Amy R, Sapiro Dina, Baker Jessica E, Qin Zhaoping, Bancos Irina, Lyden Melanie L, Young William F, Wachtel Heather, Cohen Debbie L, Kürzinger Lydia, Fassnacht Martin, Luther James M, Williams Tracy Ann, Reincke Martin, Turcu Adina F, Else Tobias, Giordano Thomas J, Udager Aaron M, Rainey William E, Nanba Kazutaka
Abstract excerpt
OBJECTIVE: Recent studies suggest a unique disease profile in elderly patients with primary aldosteronism (PA), who have a high prevalence of comorbidities and low clinical cure rate post-adrenalectomy. This study aims to investigate histopathology and genetic characteristics of PA in late adulthood. METHODS: Formalin-fixed, paraffin-embedded adrenal tissue sections from 114 patients with PA who underwent...
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