Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KCNJ5-Negative Primary Aldosteronism: Histopathology and Surgical Outcomes.

Hypertension (Dallas, Tex. : 1979) - 1 May 2026

Wu Che-Hsiung, Peng Kang-Yung, Yang Ya-Wen, Chen Peng-Ying, Chen Ya-Li, Chang Chin-Chen, Lin Yen-Hung, Wu Vin-Cent

Abstract excerpt

BACKGROUND: Unilateral primary aldosteronism (uPA) is the most common surgically curable secondary hypertension. KCNJ5 mutations are frequent in aldosterone-producing adenomas, but the clinical significance of KCNJ5-negative uPA remains unclear. We investigated whether histopathologic subtypes defined by the HISTALDO (Histopathology of Primary Aldosteronism) consensus are associated with postoperative outcomes in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenalectomy
Share to G Protein-Coupled Inwardly-Rectifying Potassium Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to KCNJ5 gene

Share to Hyperaldosteronism

Share to Mutation

Share to Registries

Share to Taiwan

Share to Treatment Outcome

Source

Identifiers

PMID: 41822958
DOI: 10.1161/HYPERTENSIONAHA.125.26266

Genes

KCNJ5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KCNJ5-Negative Primary Aldosteronism: Histopathology and Surgical Outcomes.PMID 41822958Read ↗

Histopathology and Molecular Profiling of Primary Aldosteronism.Semantic proximity Read ↗

Correlation of Histopathologic Subtypes of Primary Aldosteronism with Clinical Phenotypes and Postsurgical Outcomes.Semantic proximity Read ↗

Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults.Semantic proximity Read ↗

KCNJ5 Somatic Mutations Are Associated With Better Long-term Outcomes in Patients With Unilateral Primary AldosteronismSemantic proximity Read ↗

Evolutionary Characteristics in Primary Aldosteronism Patients.Semantic proximity Read ↗

Adrenal histologic and genetic characteristics of primary aldosteronism in late adulthood.Semantic proximity Read ↗

Clinicopathologic Correlates of Primary Aldosteronism.Semantic proximity Read ↗

Characterization of a mutated KCNJ5 gene, G387R, in unilateral primary aldosteronism.Semantic proximity Read ↗

Clinical Translationality of KCNJ5 Mutation in Aldosterone Producing Adenoma.Semantic proximity Read ↗

Prevalence, clinical, and molecular correlates of KCNJ5 mutations in primary aldosteronism.Semantic proximity Read ↗

Genetic, Cellular, and Molecular Heterogeneity in Adrenals With Aldosterone-Producing Adenoma.Semantic proximity Read ↗

Unilateral Primary Aldosteronism Lacking KCNJ5 Somatic Mutations Is Associated With an Elevated Risk of New-Onset Diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.