Evolutionary Characteristics in Primary Aldosteronism Patients.

Abstract excerpt

BACKGROUND: Primary aldosteronism is predominantly caused by excessive aldosterone production from the adrenal cortex, and the aldosterone-producing structures could take many forms, like adenomas, nodules, micronodules, and so on. Most studies of primary aldosteronism were limited to the hotspot driver genes responsible for autonomous aldosterone production; however, the panoramic genetic architecture and...

Topics

Join the communities discussing this publication.

• Adrenal Cortex
• Aldosterone
• Calcium Channels, L-Type
• Exome Sequencing
• G Protein-Coupled Inwardly-Rectifying Potassium Channels