Genomic structural equation modeling reveals shared genetic structure of cardiac function and structure-function association studies of CLCNKA mutations.

Abstract excerpt

Cardiac dysfunction is a prevalent feature of multiple cardiovascular diseases, driven by a complex genetic architecture coordinating structural and functional traits. However, systematic dissection of multidimensional cardiac function phenotypes remains scarce, highlighting the need for integrative models to uncover shared genetic mechanisms. We combined genome-wide association study (GWAS) summary statistics...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genome-Wide Association Study
• Share to Genomics
• Share to Linkage Disequilibrium