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Article

Precision medicine for atherosclerotic cardiovascular disease: Integrative genomics maps risk loci and AI-predicted functional consequences.

Clinical and translational medicine - 1 Jul 2026

Fu Liwan, Han Xiaodi, Liu Qin, Wang Yuquan, Hu Yue-Qing

Abstract excerpt

BACKGROUND: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global morbidity and mortality, but its genetic architecture remains incompletely understood. This study aims to uncover novel genetic insights into ASCVD through multivariate genomic analysis and molecular structure predictions. METHODS: We analysed genomic data from over 3.8 million individuals across various ASCVD phenotypes,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42427177
DOI: 10.1002/ctm2.70732
PMCID: PMC13351343

Genes

DCLRE1B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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