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Article

Genetic Diversity of Vif and Vpr Accessory Proteins in HIV-1 Group M Clades.

Viruses - 15 Jan 2026

Galzitskaya Oxana, Lebedev Aleksey, Antonova Anastasiia, Mezhenskaya Ekaterina, Glyakina Anna, Deryusheva Evgeniya, Likhachev Ilya, Kuznetsova Anna

Abstract excerpt

Vif and Vpr are HIV-1 accessory proteins that create optimal conditions for viral replication. They are considered as potential targets for the development of therapeutic agents. Natural amino acid substitutions in these proteins have previously been associated with disease progression. The aim of this study was to analyze the genetic diversity of Vif and Vpr in HIV-1 group M clades. A total of 5286 sequences...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to HIV Infections

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Share to vif Gene Products, Human Immunodeficiency Virus

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Source

Open in PubMed Open full text

Identifiers

PMID: 41600877
DOI: 10.3390/v18010116
PMCID: PMC12846688

Genes

APOBEC3G

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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