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Article

Sequence variability in p6 gag protein and gag/pol coevolution in human immunodeficiency type 1 subtype F genomes.

AIDS research and human retroviruses - 1 Jul 2013

Rossi Andres H, Rocco Carlos A, Mangano Andrea, Sen Luisa, Aulicino Paula C

Abstract excerpt

Polymorphisms occurring at the p6gag protein of HIV-1 have been previously found to have an impact on viral fitness and antiretroviral (ARV) resistance, mainly on subtype B genomes. We compared p6gag variability in a large group of 165 subtype F gag-pol sequences, with 36 subtype B sequences from the same study source, and identified sites of gag-pol coevolution under ARV selection pressure. Subtype-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23458243
DOI: 10.1089/aid.2012.0311

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