Article
Genetic Diversity of HIV-1 Gene vif Among Treatment-Naive Brazilians.
AIDS research and human retroviruses - 1 Sept 2017
Villanova Fabiola, Barreiros Marta, Janini Luiz Mário, Diaz Ricardo Sobhie, Leal Élcio
Abstract excerpt
HIV-1 has the Vif protein, which binds to human antiviral proteins APOBEC3 to form complexes to be degraded by cellular proteolysis. To further explore HIV-1 diversity at the population level, we analyzed blood samples from 317 treatment-naive patients in Brazil. In this study, we explored the correlations of Vif polymorphisms with clinical parameters of the patients and found that mutation K22H is associated...
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