Article
Genetic diversity in the partial sequence of the HIV-1 gag gene among people living with multidrug-resistant HIV-1 infection.
Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2024
Alencar Cecília Salete, Sabino Ester Cerdeira, Diaz Ricardo Sobhie, Mendrone-Junior Alfredo, Nishiya Anna Shoko
Abstract excerpt
The group-specific antigen (gag) plays a crucial role in the assembly, release, and maturation of HIV. This study aimed to analyze the partial sequence of the HIV gag gene to classify HIV subtypes, identify recombination sites, and detect protease inhibitor (PI) resistance-associated mutations (RAMs). The cohort included 100 people living with HIV (PLH) who had experienced antiretroviral treatment failure with...
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