Article
HIV-1 Vif protein sequence variations in South African people living with HIV and their influence on Vif-APOBEC3G interaction
11 Dec 2023
Abstract excerpt
PURPOSE: Despite extensive research, HIV-1 remains a global epidemic with variations in pathogenesis across regions and subtypes. The Viral Infectivity Factor (Vif) protein, which neutralizes the host protein APOBEC3G, has been implicated in differences in clinical outcomes among people living with HIV (PLHIV). Most studies on Vif sequence diversity have focused on subtype B, leaving gaps in understanding Vif...
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