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Article

Prognostic Impact of RAS and TP53 Mutation Profiles in Metastatic Colorectal Cancer.

Medicina (Kaunas, Lithuania) - 9 Jan 2026

Duygulu Mustafa Emre, Karaman Elanur, Karakullukçu Serdar, Aydın Mungan Sevdegül

Abstract excerpt

Background and Objectives: Our study aimed to investigate the effect of RAS and TP53 mutations, either alone or in combination, on survival in patients with metastatic colorectal carcinoma (mCRC). Materials and Methods: Patients diagnosed with mCRC and followed up at our center between January 2019 and November 2023, who underwent somatic mutation analysis via next-generation sequencing (NGS) testing, were...

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Identifiers

PMID: 41597425
DOI: 10.3390/medicina62010136
PMCID: PMC12843722

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TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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