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Article

First-line treatment efficacy and prognostic model in RAS-mutant metastatic colorectal cancer: a real-world study.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Sept 2026

Yin Wenfeng, Wu Xue, Li Tuhua, Yuan Zan, Qin Lingling, Li Qiyun

Abstract excerpt

OBJECTIVE: This study aimed to construct and validate a dedicated prognostic model for patients with RAS-mutant metastatic colorectal cancer (mCRC) using real-world data from two centers and explore the differences in the efficacy of first-line standard chemotherapy regimens in this population to provide an evidence-based foundation for individualized prognostic assessment and the selection of first-line...

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Antineoplastic Combined Chemotherapy Protocols
Bevacizumab
Capecitabine
Colorectal Neoplasms
Genes, ras

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proportional Hazards Models

Treatment Outcome

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PMID: 41806240
DOI: 10.1007/s12094-026-04301-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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