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Article

Clinical impact of TP53 mutation status on survival outcomes in metastatic colorectal cancer.

Revista da Associacao Medica Brasileira (1992) - 1 Jan 2026

Yıldız Oğuzhan, Bozcuk Hakan Şat, Eryılmaz Melek Karakurt, Araz Murat, Gürbüz Ali Fuat, Yıldırım Mahmut Selman, Artaç Mehmet

Abstract excerpt

BACKGROUND: The prognostic value of TP53 mutations in metastatic colorectal cancer remains unclear owing to inconsistent findings in the literature. Given its central role in tumor biology, clarifying the impact of TP53 status on survival outcomes is clinically relevant. METHODS: This retrospective cohort study included 115 patients with metastatic colorectal cancer who underwent TP53 mutational analysis using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41919885
DOI: 10.1590/1806-9282.20250998
PMCID: PMC13035191

Genes

TP53
BRAF
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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