Article
Analysis of TNFSF13B polymorphisms and BAFF expression in rheumatoid arthritis and primary Sjögren's syndrome patients.
Molecular genetics & genomic medicine - 1 Jun 2022
Santillán-López Enrique, Muñoz-Valle José Francisco, Oregon-Romero Edith, Espinoza-García Noemí, Treviño-Talavera Beatriz Alejandra, Salazar-Camarena Diana Celeste, Marín-Rosales Miguel, Cruz Alvaro, Alvarez-Gómez Jhonatan Antonio, Sagrero-Fabela Nefertari, Cerpa-Cruz Sergio, Palafox-Sánchez Claudia Azucena
Abstract excerpt
BACKGROUND: The increased expression of B cell-activating factor (BAFF) has been linked to autoantibody production in autoimmune diseases (ADs). The aim of this study was to investigate the association among TNFSF13B gene (OMIM: 603969) single nucleotide polymorphisms (SNPs), TNFSF13B mRNA, and soluble BAFF (sBAFF) expression in patients with rheumatoid arthritis (RA) and primary Sjögren's syndrome (pSS). The...
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