Article
Epigenome-Wide Analysis Identifies Pollution-Sensitive Loci in Fibrotic Interstitial Lung Disease
20 Jun 2025
Abstract excerpt
Abstract Rationale Particulate matter ≤2.5 μm (PM2.5) adversely impacts patients with fibrotic interstitial lung disease (fILD). Objectives We sought to determine whether PM2.5-associated epigenetic alterations contribute to the environmental pathogenesis of fILD. Methods A retrospective two-cohort study applied satellite-derived PM2.5 and constituent exposure matching to the residential location of patients with...
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