Article
Association between air pollution exposure and increased chronic kidney disease risk: the modifying effects of genetic susceptibility, transcriptomic, and proteomic signatures.
BMC medicine - 9 May 2026
Lu Jian, Sun Shuaigang, Shang Xinru, Deng Zekai, Wang Shunwei, Jiang Shimin, Li Wenge
Abstract excerpt
BACKGROUND: Air pollution exposure is increasingly recognized as a risk factor for chronic kidney disease (CKD), but the underlying mechanisms, especially the complex gene-environment interactions as reflected in genetic susceptibility, transcriptomic, and proteomic signatures, remain to be elucidated. METHODS: We conducted a large-scale prospective cohort study including 330,002 UK Biobank participants with an...
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