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Article

ALKBH1 Gene rs6494 T>A Polymorphism Decreases Wilms Tumour Risk in Chinese Children.

Journal of cellular and molecular medicine - 1 Sept 2025

Deng Changmi, Zhou Haixia, Zhang Na, Chen Min, Hua Rui-Xi, Cheng Jiwen, Li Suhong, Zhang Jiao, Ruan Jichen, Fu Wen, He Jing, Liu Guochang

Abstract excerpt

Wilms tumour (WT) is the most predominant renal carcinoma that affects children, and the understanding of the genetic mechanisms underlying WT development is continually evolving. The role of the demethylase ALKBH1, which is known for its association with diverse cancers, in WT has never been explored. Here, we aimed to investigate the associations between genetic variants of ALKBH1 and WT risk in Chinese...

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Source

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Identifiers

PMID: 41017026
DOI: 10.1111/jcmm.70864
PMCID: PMC12476963

Genes

ALKBH1
ADCK1
SNW1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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